It's funny, when folks see me using SlickRun, they always notice that I've bound it to Windows-R, replacing the standard Start|Run dialog.
This is one of the questions I get the most often. Unfortunately it's not very well documented in SlickRun, and if you try to set it via the options dialog, you'll get get a a message saying it can't grab the global hotkey.
You have to open SlickRun.ini in C:\Documents and Settings\username\Application Data\SlickRun and add an option under the [General] section "GrabWinR=1". I also like to set ChaseCursor=1 so SlickRun will come up under the current mouse cursor position.
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